大发快三高手计划

    

梁鑫 博士

研究员/准聘副教授


1999-2003 学士     上海交通大学
2003-2007 博士      上海交通大学
2008-2014 博士后     马普细胞生物学和遗传学研究所
2015-2019 研究员/准聘助理教授(博导) 清华大学生命科学大发快三高手计划
2015-2019 马普国际伙伴小组组长  
2019-  研究员/准聘副教授(博导) 清华大学生命科学大发快三高手计划

 

●  研究兴趣、领域:


1. 细胞骨架动力学及其调控的分子机制
2. 果蝇基于细胞骨架的机械力信号转导的分子基础

●  开设的课程:


《生理学》,48学时,春季学期,本科生必修专业课

●  代表性论文:


主要论文:

1.Sun, L., Cui, L., Liu, Z., Wang, Q., Xue, Z., Wu, M., Sun, T., Mao, D., Ni, J., Pastor-Pareja, J.C. and Liang, X.* (2021). Katanin p60-like 1 sculpts the cytoskeleton in mechanosensory cilia. J Cell Biol 220. (cover featured article)

2.Li, S., Wan, K.Y., Chen, W., Tao, H., Liang, X.*, and Pan, J.* (2020). Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas. Elife 9.

3.Song, Y., Zhang, Y., Pan, Y., He, J., Wang, Y., Chen, W., Guo, J., Deng, H., Xue, Y.*, Fang, X.*, and Liang, X.*. (2020). The microtubule end-binding affinity of EB1 is enhanced by a dimeric organization that is susceptible to phosphorylation. J Cell Sci 133.

4.Sun, T., Song, Y., Dai, J., Mao, D., Ma, M., Ni, J.Q., Liang, X., and Pastor-Pareja, J.C*. (2019b). Spectraplakin Shot Maintains Perinuclear Microtubule Organization in Drosophila Polyploid Cells. Dev Cell 49, 731-747 e737.

5.Sun, L., Gao, Y., He, J., Cui, L., Meissner, J., Verbavatz, J.M., Li, B., Feng, X., and Liang, X.*. (2019a). Ultrastructural organization of NompC in the mechanoreceptive organelle of Drosophila campaniform mechanoreceptors. Proc Natl Acad Sci U S A 116, 7343-7352. (Highlighted in Faulty 1000)

6.Liang, X.* (2019). Microtubule nucleation and dynamic instability in interphase fission yeast. J Mol Cell Biol 11, 941-943.

7.Shi, P., Wang, Y., Huang, Y., Zhang, C., Li, Y., Liu, Y., Li, T., Wang, W., Liang, X., and Wu, C.* (2019). Arp2/3-branched actin regulates microtubule acetylation levels and affects mitochondrial distribution. J Cell Sci 132.

8.Liang, X.*, and Howard, J.* (2018). Structural Biology: Piezo Senses Tension through Curvature. Curr Biol 28, R357-R359.

9.Liang, X.*, and Howard, J.* (2017). Structural Biology: A Force-Sensitive Ion Channel Springs to Life. Curr Biol 27, R1017-R1020.

10.Feng, S., Song, Y., Shen, M., Xie, S., Li, W., Lu, Y., Yang, Y., Ou, G., Zhou, J., Wang, F., Liu, W. Yan, X.*, Liang, X.*, and Zhou, T.* (2017). Microtubule-binding protein FOR20 promotes microtubule depolymerization and cell migration. Cell Discov 3, 17032.

主要论著:

1. Liang X*, Sun LD and Liu Z, Mechanosensory Transduction in Drosophila Melanogaster. Springer. BOOK ISBN: 978-981-10-6525-5. DOI: 10.1007/978-981-10-6526-2.

●  荣誉、奖励及参加学术团体的情况:


2015-               马普伙伴小组奖励计划   

●  联系方式:


邮件:xinliang@tsinghua.edu.cn
Orcid ID: https://orcid.org/0000-0001-7915-8094/print